IBCuprofen 

When somebody slips an ibuprofen into your root beer (preferably IBC) and watches you collapse due to the side effect of drowsiness. They then proceed to draw a stupid-looking mustache on your face with a Sharpie. Great for parties, not so great for date nights

Jason: Yo, did you see Lorenzo last night at the party? The dude had the funniest looking mustache ever
Mike: I heard somebody slipped two Ibuprofen pills in his root beer because he wouldn't drink the vodka
Jason: So, he was IBCuprofened
Mike: Totally

IBCuprofen by Isaac Taylor September 20, 2019

ibuprofen

Ibuprofen is a nonsteroidal anti-inflammatory drug.
Basically, what that means is it stops inflammation and fevers.
For the more knowing, it inhibits things called cyclooxegenases.
Mainly, cyclooxygenase-2.
Cyclooxygenases make things called prostaglandins; they promote pain and inflammation.
With less cyclooxygenases, less prostaglandins.

The difference is it actually fucking works, unlike other OTC painkillers like Tylenol (acetaminophen) or Aleve (naproxen).
Seriously, 400-600 mg (two-three Advils, its brand name) will euthanize a headache.
Not sure how it works for muscle/joint aches, but holy fuck, is it good for headaches.
Fuck Tylenol, that shit harms your liver.
Not sure how good Aleve works, but it probably sucks.

It is worth noting that all NSAIDs except aspirin have issues with raising blood pressure and harming the heart with chronic use, as well as digestive tract problems. This includes ibuprofen.

Also, you can make a topical medicine out of ibuprofen gel capsules.
Use only one capsule at a time until you find out the right strength.

Take one GEL CAPSULE of ibuprofen.
Break it with a thumbtack, small-pointed knife, or pair of scissors.
Pop the contents into one cup, then take some lotion.
Mix it with one kitchen spoon of the lotion.
Add 3-4 drops of orange oil to increase absorption through skin.

Peace.

My migraines acted up, but the pharmacy didn't get my prescription in time, so I just picked up some ibuprofen.

ibuprofen by jacrispy vulcano is my mom January 19, 2018

ibuprofen

This is a drug belonging to the group of Non-Steroidal Anti-inflammatory Drugs (NSAIDs) and are used mainly for pain relief (analgesic). The main mechanism by which these drugs work is by inhibiting cyclo-oxygenase (COX) which prevents the production of prostaglandins.

Mazzy says: "My head hurts"...
Porousi says: "have some ibuprofen babe, it will fix you right up"..
Mazzy says: "OK"

ibuprofen by Soriam November 8, 2007

ibuprofen

An orally taken, general, non-opiate, painkiller commonly sold as Advil. Common dosage is 200mg. Often referred to as <Vitamin I>.

I had a killer headache so i took two ibuprofen.

ibuprofen by Jesse Hertz December 21, 2006

Ibuprofen

Code word to be used for “sex.”

Man: “I need some ibuprofen...”
Woman: “I’ve got some in my apartment...”

Ibuprofen by BenStumpin June 20, 2019

Ibuprofen

A painkiller, usually used in a sentence when someone has a serious migraine or is seriously pissed off.

Person 1: *talks obnoxiously about some random bullshit*
Person 2: If you don't shut up, I'm going to have to take some high doses of ibuprofen .

Ibuprofen by Fuckoffemilie November 2, 2018

ibprofen 

A pill taking by mexican whores to relieve the pain from the multiple injuries caused by their pimps and plethora of customers (a.k.a. dudes that plow them like a black man plows a field). Believed to have originated in Ancient Greece and first developed by Hippocrates.

Slut #1: Ay chica, you gots any ibprofen?
Slut #2: What for, chola?
Slut #1: I only fucked thirty-five guys last night, so my pimp beat me with his cane.
Slut #2: Damn gurrrrllll, I know da feeling.

ibprofen by awesomesauceover9000 April 15, 2010