1) An alternate to 'motherfucker' to the impersonal; more accurately directed at inanimate objects and situations, whereas motherfucker is generally reserved for person-to-person communications.
2) A dire situation or circumstance.
3) Short for 'the mother of all bitches'.
A guy in his early 20s who is in an entry level white collar position. He earned his first paycheck and is hoping for a promotion. He shows up on Monday, with a new wardrobe from a discount store, thinking he’s the shit.
Check out Harold, he showin’ up like he some Kenneth Cole Motherfker! Musta got a promotion. I guess auto insurance doin’ right.