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Manafucked

When you're at an incredibly great advantage (such as being wealthy, connected, or mana-full) but can do jack shit with it because an opponent renders your advantage meaningless.
*Paul Manafort gets his accounts frozen and co-conspirators indicted because he didn't know about the secret wire-tapping.*

NEWSPAPER HEADLINE: Mueller Manafucked Manafort

megafuckjob

When you haven’t just been slightly screwed but royally fucked, usually by a large company or a sociopath.
That embarrassing megafuckjob came out of left field, I never once saw it coming.
megafuckjob by Dr Bunnygirl February 1, 2019

megapuckerpants

When your pants slowly become sucked into the crevice between your ass cheeks as you’re walking, eventually actually fully disappearing into the anal cavity until you are naked from the waist down.
I was actually horrified enough when I had experienced just regular puckerpants, but when I later endured the tragic megapuckerpants, I had been out to dinner with my in-laws and felt that I wanted to practically die from the humiliation!
megapuckerpants by Dr Bunnygirl October 9, 2019

magafucker 

Die-hard supporter of Donald Trump. Portmanteau of "MAGA" (Make America Great Again) and "motherfucker"
Those magafuckers would deport their own parents just to piss off the liberals
magafucker by shroom42 May 10, 2017

Megafuck 

Used as an extreme of the word "Fuck". You would use it in any situation where you would use the word "Fuck". Or just simply insert it into any sentence replacing the noun, adjective, or verb. Makes 'em know you ain't megafucking kidding.
Adjective:

That guy's a megafucking loser!
Noun:

That party was such a megafuck!
Verb:

Dude, I totally megafucked Jessica last night!

I megafucking hate getting a dirty sanchez!

Manafucked

Adj. Modern variant of FUBAR. Portmanteau of "manafort" and "fucked." Describes someone who is fucked beyond fucked, e.g. Paul Manafort facing a massive jail sentence due to voluminous evidence of serious felonies.
Paul Manafort had more than 30 overseas accounts.I'm laughing so hard right now I'm crying, this guy is screwed, he's manafucked. -@MrFilmkritik
Manafucked by Wes Marley August 1, 2018