1) To completely undermine or destroy anything (up to and including a nation) through untiring dedication to your god, your friends or your own mistaken belief that you are something other than inept.
2) General moral superiority and inflexibility resulting in the fubarification of everything you get involved in
Being indirectly affected in one way or another by President Bush's poor decisions whilst in office, be that as a result of the war in Iraq, the economic depression, etc.
The state of the planet after five years of the current occupant of the White House being in power. This state includes a damaged enviornment, a country that cares only for the wealthy special interestes, and where the Constitution is used to wipe the President's ass. It also includes a disastous war in Iraq, corpses piling up in the streets of New Orleans because our bastard of a President couldn't be bothered to do his duty, and a generally worsening quality of life throughout the world.