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1. To phonectically say; "stfu".
2. A shorter and quicker way to say; "shut the fuck up".
Amy: "Nick, I don't want you to cum on my face!:("
Nick: "STUFOO, bitch!"

Alicia: "But, baby, I don't want you to go out to the bar!"
Vince: "I don't care... so, stufoo."
Stufoo by RangeRov49 July 24, 2006
Related Words

stuffocated 

The feeling one gets when they have eaten so much they can hardly breathe, let alone move.

Generally when one is such a greedy shite, they put every pie eating contest in the world to shame.

This can quite often lead to a food coma for days, and possibly weeks depending on the greasiness and quantities of the food consumed.
(Ex) Husband: Wife, I am stuffocated.

Me (under my breath): That's because you ate the whole buffet out you fat bastard. Go sleep it off for a week or so. I am so embarrassed.... Can I move countries? PLEASE?
the pronouciation of the acronym STFU which means shut the fuck up. Stiffoo is just a better way of trying to say the letters, or more pg way of saying the full meaning. It also seems to lose some of its aggresion with the abbrivation.
person 1: so i was like 'blah blah blah' after she was all 'yadda yadda yadda'
person 2: god, stiffoo!

person A: stiffoo noob!
person B: why dont you just swear like a normal person?
stiffoo by anevilscientist September 22, 2007

stuffocating

The stuffocating feeling of having too much stuff. There is no more room for any more stuff; If I buy one more thing I may stuffocate. Every closet and drawer is already jammed with stuff.
The hoarder's house was stuffocating.
stuffocating by Lexi416 November 2, 2013

Stuffocated 

When you have eaten so much food and are stuffed so full that you feel like you are suffocating.
I don't think I can eat anything else, I feel stuffocated already.
Stuffocated by tlcstarfire December 29, 2012