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When a loose hoe has a dry vagina from having a sexually transmitted disease.
That Westlake hoe Amber is drydup!
drydup by Pissed Schlong December 30, 2016
Related Words

Drydocker 

To flush a toilet after shutting of the water supply to it so it has no water supply. Then you defecate in in the now dry bowl. The next sorry bastard comes in to use the toilet wondering what that foul odor is and tries to flush it down before he/she uses the toilet only to see that there is no water and they are SHIT out of luck on using the toilet.
The walmart got a drydocker last night and I was the poor bastard who walked in on the surprise. I tried hard to flush it, but there was no water. I wanted to vomit all over the place.
Drydocker by Don May 23, 2011
nerdy, pretend hipster asian who loves to make and bring people bacon in bed, easily convinced to do anything, life of the party
drydon! bring me some fuckin' bacon!!
drydon by welovedrydon February 5, 2010
why is maddy being a drydo
drydo by jimmy stevan October 27, 2016

Drydenitis 

Engaging in the act of masturbating with dish soap causing your nut sack to dry out, turn red & peel.
"Damn it Mike, stop using dish soap while wacking off..... Now you have Drydenitis."
Drydenitis by Coonetta November 2, 2008

Drydopedia 

When an individual named Dryden thinks they know everything that is to be known far and wide and will not hesitate to tell you of there superior knowledge.
This information may however not be based on fact and largely imaginary.
'That Dryden sure talks a lot of shit but acts like he knows a lot.'
'I know, God damn drydopedia.'
Drydopedia by Zoogo March 22, 2021