Tistico Share definition Flag A name used to call someone "autistic," though not in a literal sense (hence TISTICo). Tistico tried to run down the hill fast, but forgot it was covered in snow and slid halfway down it. Tistico by enemy_of_heimer February 27, 2017 0 0 Get merch Get the Tistico mug. Buy Now — $32.95 See more merch