To have sex, usually with a stripper.
From season 8, episode 3 of
The Simpsons "Separate Vocations" the
euphemism is used in regards to Mayor Quimby having sex with a mistress in a motel room.
Later used in season 3, episode 1 of Supernatural "The
Magnificent Seven" in reference to Dean Winchester having sex with a stripper or strippers. It does not mean to suck dick, Destiel shippers.