The act of getting fucked up on pills. Said pills can include Vicodin (hyrdocodone/apap), Norco (stronger hydrocodone/apap) Oxycotin (Oxycodone), Xanax (Alparazolam) etc. This is when you are in a complete state of being fucked up from taking pills, either orally, inter nasally, or even anally.
gnawledge n. (word-portmanteau: gnaw + suffix ledge; cf. knowledge) mechanical knowledge that is obtained by "gnawing" facts rather than conceptually interpreting them.
When Bacon pronounced "knowledge is power," he meant realknowledge, not gnawledge.