A female that has had sex (esp. unprotected) with many, many different guys. This "slutload" usually has bleach-blonde hair, wears low-cut shirts (as to show off their giant tits), discusses to her classmates the number of guys she's blown, talks in a sexual manner most of the time, and has many slutload friends. These females should be avoided at all costs. They usually think they're cool because they listen to Dance Gavin Dance, The Devil Wears Prada, Attack Attack!, 3OH!3, and other lame bands.
Joshua: "Wow, that girl Kendra sure is a SLUTLOAD"
Sebastian: "She sucked your dick, too?!"
Joshua: "Yeah man. And hey, did you get that naked picture of her?"
When you have to pee in a movie but don’t want to miss anything, and must do the following mental equation: will the amount I have to pee cause enough discomfort to diminish my attention capacity for the remainder of the movie to an extent which is greater than the amount of the movie I would miss by making a mad dash to the restroom.
I saw Satantango last night, wonderful film but by the 5th hour I had to start doing pee calculus.
Short-hand for the word floccinaucinihilipilification, meaning the estimation of something as valueless (encountered mainly as an example of one of the longest words in the English language).