Nigganati Share definition Flag Nigganati is a slang word for Cincinnati. Said word came into being due to the abundance of "niggas" in the Hamilton County area. I'm heading to Nigganati to pick up some "dog." Nigganati by Sir Semaj Gunoowski November 2, 2011 0 0 Get merch Get the Nigganati mug. Buy Now — $32.95 See more merch