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Surgical removal of the penis; usually due to cancer.
In a partial penectomy, part of the penis is removed. In a total penectomy, the whole penis is removed.

e-penectomy 

The instantaneous removal of one's e-penis.
Person A: Did you see that level 43 guy get owned by that level 2 noob in Halo last night?
Person B: Yeah, talk about an e-penectomy.
Me: Fuck Halo, and fuck you for talking about it every 3 seconds.
e-penectomy by scottmale24 October 23, 2005
What my boyfriend needs.
Maybe a penectomy would solve my sorry ass boyfriend's problems!
penectomy by Julia November 19, 2003

Pedidectomy

Procedure that is the removal of someone's foot from another's ass!
"you better watch yourself or your gonna end up needing a Pedidectomy soon"
Pedidectomy by NO FILTER BITCH86 December 11, 2018

international penectomy day 

April 10th oh you know what day it is time to cut that dick off
oh man it's April 10th hide your dick or someone's gonna cut it off cause it's international penectomy day

five dollar penectomy 

when a girl gets so pissed off that she slices off a man's penis with a pocket knife.
"He cheated on me, so I gave him a five dollar penectomy"