mcguirel 

In the Trainz RR Sim world this is commonly referred to as cunt, bitch, whorebag, dbag, etc

Dude stop being a fucking mcguirel

mcguirel by EpiCFail2011 May 31, 2011

Spunk McGuire 

When one party ejaculates in his hand and disperses the semen in another parties face in a spider man web motion.

John: I was fed up with my roommate so I came on my hand and threw it in his face like spider man shoots his web.

Adam: Oh! So you Spunk McGuired him?

Spunk McGuire by Jmac1101 December 31, 2021

Lizzie McGuire fabulous

An adjective used to describe someone whose outfit fabulously embodies the early 2000s aesthetic. A reference to the early 2000s tween fashions worn by Hilary Duff as the star of the Disney Channel series Lizzie McGuire

“I love what you are wearing. A true throwback to the early 2000s. 100% Lizzie McGuire fabulous!”

Lizzie McGuire fabulous by TK2000 October 29, 2023

McGuired 

The ultimate level of intoxication. This happens beyond the blackout stage, and can cause one to do ricidulous, unexplainable things. When McGuired, one often does not wake up in their but, but often on their couch or kitchen floor.

Q: Are you going out tonight?
A: Yeah, but I don't want to drink so much that I get McGuired

McGuired by mcguire4313 October 14, 2008

Stinky McGuire 

To have someone's (or more specifically, a friend's) back.

"Back home, we call that having a friend's back."
"Well, back in my day, we called it pulling a Stinky McGuire!"
-Hop Pop, Amphibia

Stinky McGuire by Fumbells August 14, 2021

lizzie mcguire 

a 15 year old girl who has her own tv show about her perfectly good life that is suppose to be horrible.

lizzie mcguire by malora May 5, 2003

Pierre McGuire, Nohomo 

nohomo is a phrase that is uttered after a person, often unintentionally, makes a statement or action which, out of context, may seem homosexual in nature.

Pierre McGuire, the queen of NBC, has become known as a gay icon in an otherwise completely straight world. His use of giddy hyperbole in reference to a players abilities or traits, seldom using the phrase 'nohomo', has contributed to his name itself becoming a 'homosexual utterance' and so when mentioned in conversation by a straight man, must be followed by 'nohomo' to ensure said man's sexual orientation.

Use of Pierre's name without 'nohomo' is enough to make the boys question your lifestyle.

Marty: Man, did you hear what Pierre Mcguire, nohomo, said last night?
Doug: Yea dude, Pierre, nohomo, is a total boneshow for anyone in skates.

Pierre McGuire, Nohomo by WesleySnipez88 June 30, 2012