A person who is very good at being awesome, The person enjoys being good at everything he/she does
if McGuire is a girl she is very attractive and all they guys love her

if McGuire is a boy, then well get ready for a suprise downstairs ;) RAWR
Wow, I wish I was a McGuire
by Frankie Mollcer November 13, 2009
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A location through the years of 1999-2003 that was once considered the drinking capital of Philadelphia. Many have gathered on numerous pointless occasions and have attained extreme levels of intoxication. From beer bongs to birthdays, whippets to gankers, attractive high school dreams to sloppy second scravens. It was a night of chance and garunteed inevitable blackouts. Mainly goodtimes.
"After school McGuire!"
by Jim Christy and mangs May 9, 2007
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sucking your own weiner for a long period of time before cumming on your face while fingering your butthole
that kid definitely mcguires himself
by anonymous 11111 June 12, 2009
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A person who pretends to drink a lot an act drunk. But in reality is a lightweight.
Man your such a mcguire, you can't even take shots without mixing them in your water bottle.
by qwerty429 October 21, 2011
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One of several nuclear plants along the Catawba River. Folks associated with this plant have the power to shoot anybody they feel threatened by. The sheriffs office tells them it's okay to handle a problem with a gun that you should be handling with your two hands.
If you think McGuire Nuclear Station has that kind of power, you don't know the first thing about us.
by Solid Mantis February 6, 2018
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The ultimate level of intoxication. This happens beyond the blackout stage, and can cause one to do ricidulous, unexplainable things. When McGuired, one often does not wake up in their but, but often on their couch or kitchen floor.
Q: Are you going out tonight?
A: Yeah, but I don't want to drink so much that I get McGuired
by mcguire4313 August 20, 2008
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Being so high that a person acts like a dinosaur, usually a stegosaurus. Usually will indicate a severe mental problem. Sometimes the McGuired will also ramble on about nothing, and make some of the stupidest remarks ever made.

Relates to how stegosauruses were so stupid they would run off cliffs in such massive numbers that their corpses would make a slope that could be used to go down the cliff safely. Yet most stegosauruses still jumped off the cliff. Stegosauruses are one of the stupidest creatures ever, dieing at a rate of 30% total population a year. Only 5 true stegosauruses remain today.

Also relates to Dr. Brandon R. McGuire who argued that stegosauruses primary source of food was marijuana which lead to them having a walnut sized brain.
"He's so McGuired that his tail is showing"
by StegoMaster October 27, 2009
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