Duff

to throw a severe beating to another person or group. Used with mal intent or to beat the ass's of.

"If you don't shut the fuck up, i'm gunna duff your dumb ass"

by DamionFK December 02, 2006

Duff

A real term used in the heydays of Cocaine frenzy, 70s, 80s. Duff refers to that portion of your cocaine that consists of powder only, usually full of cut or anything else but real cocaine.

Shit, I won't buy from that dude again, this is all duff.

by Gojai August 30, 2017

Duff

Designated,ugly,fat friend.

You don't necessarily have to be fat,or ugly to be one. the duff is considered a duff when he/shes significantly less attractive out of the group of friends they hang out with and both boys and girls can be one.
They are often used to get information about his/her friends.

1# "Damn, those girls are hot...well except for that one"
2#"yeah..maybe we can get some info on them from her?"
also shown in the movie"The Duff" if you need a visual example.

by Guade April 02, 2015

Duff

v. the act of punching someone in the face.

"Yo did you see Hilton duff Chino in the face"

"Chino is bleeding because he got duffed so hard"

"Some would should duff that kid, Chino, in the face"

by Douch B. September 28, 2007

Duff

The leftover weed from a depleted vaporizer. It is often used to make canna-butter or sprinkled on food as an edible, since the the THC has been activated by the heat of the vaporizer.

Stoner 1: Damn, we’re out of weed!
Stoner 2: I got this duff , we could just eat some of that.

Stoner 1: Aw, hell yeah, let’s get blazed.

by teaoutdoors June 17, 2021

Duff

Scottish slang for a vagina

Also means something is rubbish, crap or broken

I'll kick you in the duff

That's totally duff

by Freakosaurus November 18, 2006

Duff

the act of locking the door behind you when you arrive to your place to lockout someone who may intrude or barge in unexpectedly.

"Hey did you duff the lock? Yeah man, don't worry I duffed it."

by Pants007 January 20, 2009