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Usually seen on YouTube videos, the "me:" is a way to show a point you want to make in a conversation example. When you write the "me:" you tell the readers to watch the video, pretty much saying that this is your response.
You watch a video of someone raging and you go to the comments section and write a comment such as this:
"Me: "I'm going to win this match!"

Another player kills you

Me: "
me: by JabbaTheTrump May 31, 2018
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someone who looks themselves up on Urban Dictionary
Me by You Kow It's True December 16, 2012
Related Words
I am me.

You are you.
Me is me.
You is you.
We are we.
That's not the case tho.

The point is.
Me=the writer (me)
You=the person reading this right now(you)
so stop looking up "me" when it's all about me!
Me by X2liTx September 8, 2016
Me by PotatoWhat December 3, 2016
You actually thought it's a good idea to look me up on urban dictionary? Wrong choice.
me by 32121 January 26, 2016
Command in IRC that shows the author's name followed by any text after the command. Typically used to describe an action performed by the author in the third person. When read in an online forum, it is usually meant to be humorous.
In IRC, if my name is NeSe:
/me kicks you in the balls!
becomes
* NeSe kicks you in the balls!

You are then supposed to imagine that I actually did kick you in the balls.
/me by NecroSen March 11, 2005