The lack of character or poor quality of a person when they are never able to be average or more than most people. It's pretty sad when someone is cursed with this.
by von groovy May 11, 2019
Get the lessence mug.An insult generally used to call another person stupid. Derives from the medical term for smooth-brainedness (lissencephaly). A harder-hitting form of the term "smooth-brain."
Adam: If pro is the opposite of con, what is the opposite of progress?
David: Dude, you're such a fucking lissencephaloid.
David: Dude, you're such a fucking lissencephaloid.
by Bigolebenis November 5, 2022
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Guy 1: Hey you know that guy Dan?
Guy2: Yea, what about him?
Guy1: He must have lissencephaly or something because everything he says is total BS
Guy1: Agreed, Dan is smooth-brained
Guy2: Yea, what about him?
Guy1: He must have lissencephaly or something because everything he says is total BS
Guy1: Agreed, Dan is smooth-brained
by BJBone July 12, 2021
Get the lissencephaly mug.someone who looks down on you for not being up to their personal standards, be it age, race, or personal choices.
older guy: that kid over there was tryin to talk to me about politics, but i blew him off.
younger guy: wow what a lessener of you
younger guy: wow what a lessener of you
by lil' snoopy November 29, 2009
Get the lessener mug.Creighton Lessenberry's usually someone who fits into most all groups in school. Creighton has good manors towards adults and a great since of humor. Puberty hit him like a truck in middle school and girls tend to fall for him whenever they make eye contact.
by Clessenberry May 18, 2017
Get the creighton lessenberry mug.by anonymous December 29, 2022
Get the Lissencephalic mug.