This occurs when a woman's boobs, or tits become irritated due to chafing of a shirt, the pain that follows running without a bra, or excessive activity of any kind.

Not to be confused with nipplitis.
Damn Julie, I got a bad case of irritits!
by st. ale September 15, 2007
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How a woman feels when she doesn't want her breasts fondled
Mildred was irrititted, yet again, when her guy started groping her swollen melons.
by Thumper12 June 26, 2014
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