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When and animal, or human, spends too much time up close to butt holes. This is common in dogs due to their continuous ass sniffing rituals. The inexperienced will inadvertently touch said butt orifice with one or both eyes ... causing a hideous eye infection. Holeyetis
What the fuck dog. Your eye is oozing again with holeyetis. Why do you keep sniffing ass so close!
holeyetis by DarthAss March 30, 2017
Related Words

Holey Banana 

The fetish sexual act of laying ones penis on a table, board, or similar surface and proceeding to stab it repeatedly with a knife or sharp object.

It is generally accepted in such fetish circles to do such a performance with a steak knife equalling or exceeding the size of the penis stabbed.
"Dude, lets get drunk and stoned and give ourselves holey bananas"
Holey Banana by xBSTx July 13, 2009

holey relic 

An old and worn-out, but cherished, piece of clothing.
Don't you dare throw out my AC/DC t-shirt. It's a holey relic!
holey relic by Two Hep Cats September 30, 2012
Outgoing and Loveable person. Caring a generous. Spontaneous.Can be a bitch, and often misinterpreted.
I saw Holley at the party yesterday and I couldent help but enjoy myself.
holley by HolleyMarie June 20, 2008

ass-holey 

To be an asshole 24/7/12/365 (366 if you include leap year).
Assholes love to be ass-holey all the damned time.
ass-holey by Lady Byron July 9, 2011

holey moley 

a phrase used in extreme disbelief, when you're speechless
H- no way! it that bowling for soup naké
J- HOLEY MOLEY!