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The word "effers" was derived from some retarded kid by the name of Alor.
The word is usually used to express annoyance, disgust, surprise, anger, irritation, contempt, or disappointment...usually in a light-hearted manner.
(Lately, this word has been favorably used using squinted eyes, a scrunched nose, and a whispery, whiny voice, all while hunching the back slightly and is usually followed by the recipient with the traditional slow shake of the head, a stupid smirk and the low mutter of the word "geek.")
Effers Example 1:
Alor: "Hey Eyuel, Samora forgot Madden at home."
Eyuel: "Effferssss!"

Effers Example 2:
Melaku: "Hey you guys, my mom said we have to leave cuz its getting dark and she wont be able to find me so I have to take the ball now."
Aklil: "But it's only 5:30! You won't disappear until 9!"
Eyuel: "Effferssss!"

Effers Example 3:
Alor: "Hey Joseph, can I borrow a dollar?"
Joseph: "Alright."
Eyuel: "Effferssss!"
Alor and Joseph: "..the heck?"
Eyuel feels stupid.
effers by Nati T July 20, 2006
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Frijsenborg Efterskole 

A very very good school with funny teachers and students.
Omg, you are so funny, are you from Frijsenborg Efterskole?
you don't like something or something/someone makes you mad or did you wrong.
Timmy stood me up and went to the movies with ashley".."thats effery..
effery by ibeatomyowndance July 4, 2010
very large f or ff cup breasts
"Dang that girl got them effeses"
effeses by the don in p'cola January 31, 2006

Effervescent 

Those fairy lights though. Effervescent.

Effervescent 

Twilight in-joke referring to a popular meme which speculates about what Edward might text Bella about.
Edward: saw a snail today... effervescent
Effervescent by Kimmy-Pie March 30, 2021
Short for mother fucker. You usually say it whenever off color language is not preferred.
Man, that roller coaster ride was an m-effer!!
m-effer by Danbridge October 11, 2006