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1) n. In New England, it is a brass musical instument, conical in construction, about 18 feet long, with a large mouthpiece, and is the lowest of the brass instruments. It replaced the ophiclede in the symphony orchestra, and has nothing to do with Wagner Tubas. It has only one direct cousin in brass instruments, that being the fluglehorn, for all other brass instruments are more cylindrical than the tuber, even the french horn.
2) n. For the rest of the English-speaking world, it is a fleshy-rooted plant like a potato or a yam. Hence, New Englanders and Non-New Englanders can get confused at times, as evidenced below.
An actual conversation:
Denny: Dan, can you play the tuber for the Bristol, RI band next weekend?
Dan: Well Denny, do you want me to play 1st or 2nd potato?
tuber by Dan1271 November 13, 2007

Tuberculosis

A disease that killed the most Bad ass character in Red Dead Redemption 2
Arthur: We are not a charity

Man: Spits on Arthur

That’s how he got tuberculosis

Tik-Tuber 

A person from or on TikTok that post's their cringe on YouTube
1: Hey did you see that new Tik-Tuber

2: How the hell would I know you didn’t specify the person there’s like a thousand

1: Oh well nevermind
Tik-Tuber by ThatDeadsoulGuyyt July 21, 2021
A swampy , incestuous red neck breeding ground located in the woodlands of Oneida County, New York between the towns of Lee Center and Camden. TABERG is best known for providing manpower to the local unemployment roles and punchlines for any joke involving public intoxication, animal pregnancy, low intelligence or meth lab explosions. The citizens of TABERG annually mass at their "Field Days" to exchange insults, chew tobacco, drink and fight. Each year the results of the previous years alcohol induced copulations are shown off and judged. Fatherhood is determined by a lottery. Tabergers are suspicious of outsiders and will confront and attack anyone they are not related to or has a full set of natural teeth.
Billy Bob: What’s got 86 legs and 14 teeth?
Cletus: I dunno
Billy Bob: The line for the Taberg Field Days beer tent!
Taberg by boonviller September 21, 2021

Tuber simulator 

A still relevant game for mobiles and the game is available for free and that’s a great price
WHHHHAAATTTT!!! You’ve never played tuber simulator??
-PewDiePie