Spermicus Share definition Flag A guy who can't hold it in...When a hot girl walks past, he loses it, usually leaving a stain on his pants. Zach:Dude Alex walked past and Vince totally pulled a Spermicus! Spermicus by way2go March 9, 2009 0 0 Get merch Get the Spermicus mug. Buy Now — $32.95 See more merch