To get sober. Or more commonly referred to quitting methamphetamines.
Hey, I'm sorry but I can't chill with you guys at the tweaker pad anymore...I'm trying to stay off-one for good.
by Fairyduster86 January 19, 2017
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To get angry, frustrated, or irritated to the point that you suffer a tantrum of sorts
Anna: How was tennis, Tim?
Tim: Rubbish. I lost to Aidan. I should try and keep a level head and not go off my rocker when I play...
Anna: Yes. One should never go off one's rocker. Now it's time to eat some squirrel pie.
Tim: :l
by TimkinsTheTimTam December 30, 2011
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Unhinged; temperamentally unsuited for one's position.
The White House staff is off one's trump; they cannot give a consistent explanation for the incriminating Russian collusion stories.
by smjgJsbjgsm August 9, 2018
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To behave in an extreme, inappropriate manner in response to provocation.
When he heard he just went 'off on one' and wouldnt stop ranting for several hours.
by terminal.eight March 5, 2006
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Off by one or OBO is a common error in computer program whereby a loop executes one time too few or too many. It occurs most commonly with complex vector or matrix scans.
Programmer 1: This program doesn't work. Take a look and see if there's anything wrong.
Programmer 2: Oh, this for loop is OBO. You aren't scanning the whole array.
by Lezard Valeth May 24, 2003
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An "Off-By-One" (OBO) in a non-programming context is the act of a touch-typist beginning to type with their hands one key offset from home position.

If the typist in question types fast enough, the resulting nonsense string of gibberish resembling a 14 year-old's SMS history or YouTube comment may actually be sent/submitted before they notice what they've done.
Ex 1:
Sm "Pgg-Nu-Pmr" )PNP_ om s mpm-ptphts,,omg vpmyrcy od yjr svy pg s ypivj-yupody nrhommomh yp yupr eoyj yjrot jsmfd pmr lru pggdry gtp, yjr jp,r ppdoyopm/ (*That was actually harder than I thought it'd be, though notice the prevalence of things like omg and gtp)

Ex. 2:
Carly1992: Wanna come over to my place?
TCAPreditorBate: rirakky!
TCAPreditorBate: totally* Sorry, off by one
by ZenAtWork May 28, 2010
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Behaviour outside the realms of normal, with respect to the individual.

To do one's own thing.

To 'give the birdie' to the world and make a concerted effort to annoy / piss off / offend as many people as possible in a given timeframe.
John: Er... is Calvin off on one?
James: Nope - he usually chases pigeons on his lunchbreak.

James: Woah - does Miranda usually dance on tables whilst inebriated, sans underwear??
John: Nope - she's off on one.
by mr. duffy March 7, 2010
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