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It's a descriptive word for a small inbred hamster/chincilla/armadillo or a mix of the three. Usually these creatures are dirty, quite often welsh and look like a disfigured pigs butt.
If you were to actually see a Manchillo you would go into shock and if you touched one you would be very ill as a lot of them carry herpies.
You filthy Machillo!

What a bunch of damn dirty Manchillo's
by IainW September 27, 2006
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