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Originating as a misspelling of the fish "guppy" or "guppies", Fuplie is often used as a swear word, especially on the online platform "tropical fish forums", often replacing the "F" word in conversation.
"My fuplies are doing well after cleaning their fish tank"

"I don't give a fuplie"
"I don't fuplie care!"
Fuplie by jb52 April 25, 2025
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Leslie Fu is a member of "Just Ends" and a female twitch variety streamer who goes by the name of Fuslie. Her community, FusFam, is a strong supporter of her who has come to call her many different names such as "jankslie", "Blindslie" and many more.

PS she is super jank and you should subscribe using Twitch Prime
Did you hear about that streamer, Fuslie?
fuslie by edisonsafo January 24, 2019
Related Words
A full beer. Used when you have finished a beer and want to replace an empty with a full beer
Hey, get rid of all these empties and bring me a fullie
Fullie by andypoirier September 7, 2013
A short term for "fucking uglier".
Dude, Paris Hilton is fuglier than her dog.
fuglier by Fox News October 20, 2006
Man, that girl is fugly, she sure is the fugliest girl I've seen today.
fugliest by The walls December 14, 2008

fullier than a mugg 

over full, ate to much
that food was good "im fullier than a mugg"
Plural for fucking ugly people presented as a noun.
I live next door to the Fuglies.
Fuglies by Marc Aaron August 3, 2006