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Short for "you know what I'm sayin'." Pronounced "ya kweese." Can be lengthened for effect. "ya kwEEEEEEESE." Not an internet acronym, but a truncated verbal form of "you know what I'm sayin'."

Correct response to 'ykwis' is not 'ikwis (I know what ya sayin') but another 'ykwis.'
"Damn, that bitch couldn't keep her mouth shut in class, ykwis ?"

Bob: "She can unfold my chair anytime, yaaaaaaaaa kwiiisss?"
Manfred: "ykwissssssssssssssss!"
ykwis by The Mroot August 23, 2009
Related Words
yakwis yakisoba YKWIS yahwist Yakistan Yahwism yakish Yakism yaksish Yakwii
Jews, Christians, or Jewish-Christians, who emphasize using the Hebrew name of Deity: "Yahweh".
Yahwists like to point out this verse to their Jewish and Christian friends:

ISAIAH 65:11,

You are those who forsake YAHWEH,
who forget My holy mountain,
who prepare a table for __________* (deity of FORTUNE),
and who furnish a drink offering for Meni (deity of DESTINY),

*You NEED to read this name as written in the ORIGINAL, Hebrew version of Isaiah.
yahwist by L. E. Yahman July 28, 2006
1. The worship of Yahweh (Biblical deity).

2. Especially by those who specifically use the name "Yahweh" when referring to the deity.
J. Golden is an adherant of Yahwism.
Yahwism by Isaiah Fourman March 18, 2009

Yakistan 

US Military slang for US Army's Yakima Training Center near Yakima, WA.

The terrain and climate attempt to approximate those found in Afghanistan.
Gotta pack for a two week training mission in Yakistan.
Yakistan by TomRedlion September 25, 2018
An acronym for the phrase "You Already Know What It Is". Often used online and by Michael Martinez, the swag-tastic drummer for the epic band Allstar Weekend.
Just bought my tickets for the Allstar Weekend concert. YAKWII babygurrlll.
Yakwii by AllStarSwag October 31, 2011

yakisoba 

Let's eat Japanese Yakisoba.
I cook Yakisoba at a party.
yakisoba by Ramunenakayama December 28, 2007