He's the man, the legend, the king. Ginger Elvis, King Baby Duck, and J Ho, it's all one man. He's a great dancer, likes long walks on the beach, and will fuck your day up if you cross him. He'll blow your mind with his music, then blow his load on your mom. His name is Josh Homme, and he (probably) approves of this message.
Dood 1: I just got back from the Eagles of Death Metal show.
Dood 2: SICK! Did Carlo Von Sexron seduce you with his drums?
Dood 1: Nah, he wasn't there. He was probably fucking your mom.
Dood 2: Fuck man, I wish I was as cool as him...
A neurotransmitter believed to regulate mood. SSRI's inhibit the reuptake of serotonin in the brain (leading there to be more serotonin left as a result), hopefully improving the mood.
Personally, a good blast on the Codeine cheers me up more than any SSRI.
Perhaps it's my endorphine system rather than my serotoninergic system that is fucked.
A lack of Serotonin is believed to be a cause of depression. It also controls appetite, among other things.
Antidepressants often (through various mechanisms) increase the amount of serotonin in the brain.
MDMA (Ecstacy) causes a massive (cascading) release of serotonin in the brain - responsible for both it's euphoric effects, and the depressive aftereffects (less serotonin remains in the brain, until generated again)