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No one gives a shit 

When you really really want to emphasize that no one cares about something. Not only does it feel satisfying to say, it's a quick and easy way to shut someone down when they say something stupid or trivial.
Guy 1: My favorite color is white.
Guy 2: No one gives a shit.

No Shit, Sherlock 

Used as a sarcastic comment for someone who stated the obvious, using a reference to the famous fiction detective Sherlock Holmes, it can be understood as "No way, you are Sherlock Holmes!" which can actually mean "Of course, you dumbass!".
-It's hot out there.
-No shit, Sherlock!
No Shit, Sherlock by CesarD11 November 7, 2014

No Shit Sherlock 

A phrase often used towards someone who states the obvious.
"There is snow outside, it must be cold"
"No shit Sherlock!"
No Shit Sherlock by NowhereMan November 4, 2004

no shit Conan 

The phrase "no shit Conan" refers to the phrase "no shit Sherlock", but instead of Sherlock it's Conan, the main character from the anime Detective Conan.

This phrase is the weeb version of the "no shit Sherlock".
Normie: Did you know that Conan likes Sherlock Holmes?
Weeb: No shit Conan.
no shit Conan by Karizaki January 3, 2019

No Shit September 

A challenge of a month in September where you can't go pooping for a month. 99% people failed this challenge.
I'll be taking this No Shit September challenge to prove that I'm not a human.
No Shit September by Mlemwelp September 3, 2020

No funny shit 

For one to be serious, used around New York, it would be like saying real talk. If some hits you with “no funny shit” there about to tell the truth.
Tykeis “, no funny shit, my ma died yesterday”.

Marcus”, deadass ?”.
Tykeis “ word 2 !”.