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desolation row 

The name of a Bob Dylan song. Indicative of a place where people who do not fit into society(free thinkers and artists) go to live. It does not necessarily have a negative connotation. Often visited by posers attempting to look cool by hanging out with the real free thinkers.
He is so literary. He must be straight off of desolation row.
desolation row by asdfaskldfj September 29, 2005

italian isolation 

to be in a small shower naked with 4 italian girls while they wash eachother
"what did you guys do last night?"

"oh just some italian isolation."
italian isolation by el fen August 18, 2009

self isolation 

The act of distancing oneself from the wider public. Likely to be a result of fear of an oncoming zombie apocalypse, plague or COVID-19
Sarah pondered the on coming plague and though "f**k that, I'm off into self isolation in my camper van til it blows over"

Isolationship 

Long- or short-distance relationship between two people kept apart due to shelter-in-place constraints.
Their hot and heavy isolationship was getting weird, the limits of cyber romance coming clear. She lived three blocks away from him, they hadn't been able to see the other for two weeks, each of them trapped in their apartments.
Isolationship by Monkey's Dad April 9, 2020

Isolation 

Isolation is possibly the most boring thing in existence. It is the act of staying inside your house because you don’t want to catch a global pandemic of sort, most commonly COVID-19. It is recommended that you do isolate, even though while doing so you will probably be making TikToks or FaceTiming your toxic friends.
Have you been making TikToks and eating too much in isolation?
Isolation by it'smeyourcousin April 20, 2020

Desolation 

To be utterly annihilated to be destroyed nothing else left
You'll know when you meet desolation.
Desolation by Desolation January 20, 2015