Something that you say you or your friend is on/smoking when he says something crazy, weird, outlandish, or if you're anxious/freaking out about anything.
"He just said the craziest thing ever, he must be on that tweaknine pack."
or
"Istg I'm on that tweaknine pack I cant stop thinking about her."
Short-hand for the word floccinaucinihilipilification, meaning the estimation of something as valueless (encountered mainly as an example of one of the longest words in the English language).
Precedes or follows either a gratuitously disrespectful or honest remark, originated in New York City. Used in similar fashion to "no offense" or "to be honest," interchangeably.
Ya mans is wild buns, respectfully. Respectfully he's washed.
After school, The Modells on Jamaica Ave was active. Respectfully.