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Swallowing, inhaling, snorting, or injecting yourself with a drug, usually one that is illegal without doctor shopping for a prescription first.
2 Strawz: You been movin bricks, $hasta?
$hasta: UOENO! Up for 24 hours with my lab coat on. Now I need to substanize my body with some alcohol STAT to wind the hell down.
by MrShasta June 06, 2013
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