pustule 

a zit or pimple with pus in it. Breaking your pustule is the same as popping it.

Bevis: Joe finally broke his pustule
Butthead: Really?
Bevis: Yea, he finally popped that enormus pimple on his forhead.

pustule by anonymous December 31, 2006

Pustule 

Noun: A hard disk shaped crust of fecal matter that forms in the anus after each defecation. This is an extremely important part of a bowel movement in that it keeps ones anus from constantly leaking liquid shit. This disk shaped piece of shit acts as an anal dam but it can be broken at great embarrassment to the host of the anus. Wrestling, Yoga and/or laughing too hard can all cause enough stress to rupture a pustule.

Did you see that trail of shit? Beirne must have broke his pustule.

Pustule by Randy Sack JC November 4, 2009

Pustule 

A single piece of pasta which isn't a noodle I.e. Penne

I love the crunch of a hard pustule.

Pustule by Dedraterdater February 14, 2023

pustule pussy

A filthy whore who has so many STD's that she gets sores, boils, and zits on her vagina, causing her to excrete pus from her genitalia.

Dude, that fuckin whore has a fuckin pustule pussy; see that shit running down her leg?

pustule pussy by Cum%Andrew%Dumpster November 6, 2007

crusty pustule 

A person that is so horrific looking that no matter how shit-faced drunk you are at the end of the night you would never go home with them no matter what.

Oh God, look at that crusty pustule at the end of the bar, he/she had better not even try to talk to me.

crusty pustule by rommate s dirty girl January 11, 2010

crusty pustule 

A person that is so horrific looking that no matter how shit-faced drunk you are at the end of the night you would never go home with them no matter what.

Oh God, look at that crusty pustule at the end of the bar, he/she had better not even try to talk to me.

crusty pustule by rommate s dirty girl January 11, 2010

Pot Pustules 

Small scraps of marijuana that are left over after the rolling of a joint and/or packing of the bowl.

Hey, Mocher, I rolled some joints in my car and now the front seat is full of pot pustules.

or

Big Daddy: Man, I wish we had some smoke.

Convoy: Yeah...

Jim: Man, when I think of all the Pot Pustules I've wasted, I'd have like a bunch'a joints and shit.

Pot Pustules by RollUmBigged July 8, 2010