Small scraps of marijuana that are left over after the rolling of a joint and/or packing of the bowl.
Hey, Mocher, I rolled some joints in my car and now the front seat is full of pot pustules.

or

Big Daddy: Man, I wish we had some smoke.

Convoy: Yeah...

Jim: Man, when I think of all the Pot Pustules I've wasted, I'd have like a bunch'a joints and shit.
by RollUmBigged July 7, 2010
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