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pharmageddon 

the over-indulgence of pharmacueticals leading to the state of complete annihilation
ted's friends realised he'd reached pharmageddon, when they found him tits up in the gutter
pharmageddon by ed reese September 30, 2006

Hamageddon 

1. The mass government sanctioned slaughter of pigs in direct response to fears of swine flu.

2. The slaughter or culling of swine populations due to irrational fear of swine flu.

3. The slaughter or culling of swine populations due to cultural biases against pork based upon religious beliefs. The slaughter of such animals alleged to be justified due to concerns about diseases such as Swine influenza but really based on deep rooted religious biases or prohibitions against eating meat from pigs.
The government of Egypt has ordered the destruction of all pigs to stop the spread of Swine Flu. The actions will result in Hamageddon for Egypt's 400,000 pigs.
Hamageddon by nycesq April 29, 2009

promageddon 

When your prom experience goes horribly wrong.
Jane was hoping for a fun night at Prom but when John came up in jeans, it was a total promageddon!
promageddon by Japolina May 25, 2016

pwnageddon 

1. Being completely dominated by an artificial intelligence that has stronger forces and superior strategies: When red conquers blue and you lose to AI.

Leet-speak slang. See pwn.

2. Possible future scenario for when AI finally outsmarts you and make you pay for all the bots you smashed while playing computer games.
A1: Robots attack!! HELP!

A2: pwnageddon!!1!

B1: DIE HUMANS!! LOL!
pwnageddon by Scancat February 16, 2010

Pimageddon 

When the last battle between good and evil prior to the Judgement Day would take place could hypothetically or unprovenly be divined from the digits of the decimal number π.
Both number theorists and biblical numerologists are hell-bent to figuring out the D-day for Pimageddon—who would be the pi futurist who stubbornly claimed to be able to predict Christ’s Second Coming, Who had already forewarned his followers that He would return to earth like a thief?
Pimageddon by Fasters December 30, 2021

Amageddon 

A fusion of AMAzon + armaGEDDON; specifically, October 13, 2017, the day the giant retailer shut down all its customer chat boards.
Becky and I used to chat all the time; but ever since Amageddon I have no way to reach her.
Amageddon by al-in-chgo August 12, 2018