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optirectalitis 

When the optic nerve in your eye begins to grow and won't stop. It grows and gets longer until it connects with your rectum this gives you a crappy outlook on life.
You can tell he has optirectalitis by the way he always thinks everything sucks.
optirectalitis by rustyacline May 13, 2009

Optirectumitis 

(see also optirectumitus)
Chronic pessimism of a particularly severe nature. Derived from opti-rectum-itis as follows:

opti: having to do with optics, visual or eyes

rectum: the innermost and center between the gluteus maximus, the primary source of shitstains and buttnuggets; butthole; fecal exit, excremental departure zone.

itis: an inflammatory disease

FACTS: When hyper-signals originating in the optical and rectal regions of the human anatomy cross at certain points and become snared and start to resonate at unusually high amplitudes, the associated neuro- transmitters merge and the combined signals release an evolutionary combination of fecal-optical gases which then propogate directly to the frontal cortex of the brain. When the fecal-optical gases settle, an unsuspecting victim will often become pissy, negative, impatient and, generally, will exhibit symtoms of being a total scumbag schmegma breath.. especially around trusted friends and family!

General Symtom: A shitty outlook on life.
Don't mess with John today. He is very discontented and angry. His misfortunes and blunders combined with the span of time since his last blowjob, have resulted in a severe case of optirectumitis.
Optirectumitis by John W. Cornett December 30, 2007

Optorectitis 

When the optic nerve gets shoved up your rectum, or, in plain terms, You got your head up your ass.
Jake Paul: Its EvEry daY bRo
Museum Tour Guide: And this, tourists, is the most severe case yet of optorectitis.
*Tourists stare in a mix of awe and disgust*
Optorectitis by Mr McSauce September 14, 2017

optirectosis 

A nervous system condition in which an optic nerve gets tangled up with an anal one, and you get a shitty outlook on life.
Man, this damn optirectosis is getting me down!
optirectosis by feefiefo February 1, 2025

optirectamitis 

Where a nerve in your eye and you ass gets crossed and you get a shitty outlook on life..
That chic has got optirectamitis.
optirectamitis by Critter wRner February 27, 2025
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