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Optirectalosis 

A medical condition consisting of a crossing of internal wiring which gives the affected person a shitty outlook on life.
John: "Life sucks."

Debbie: "You've got a bad case of Optirectalosis."
Optirectalosis by digismack April 21, 2005
Related Words

Optirectitis 

The unfortunate event of having your head too far up your ass. Another form of showing extreme ignorance.
That boy just won't learn from his mistakes. He suffers from optirectitis.
Optirectitis by Rabidone1983 October 19, 2017