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Defeat; disappointment mixed with acceptance. It is a cute way to express sadness after something unfortunate happens. Word is Japanese in origin.

Nyoro~n originated in a spinoff comic strip called "Nyoron☆Churuya-san" by Utsura Urarak, based on the character of Tsuruya from the anime "The Melancholy of Haruhi Suzumiya". The strip was later expanded into 13 two-minute episodes which are available on youtube by searching "Nyoro~n Churuya-san"; Watching one of these episodes is the best way to understand, through context, what the word means.

Nyoro~n is said in a cute, sad tone of voice after something unfortunate happens. The character who says it is a cute little girl who constantly fails to achieve what she sets out to do (often her goal is to get some smoked cheese).

People who use this word are probably either fans of the Haruhi series and its spinoff, or trying to look really cute, or both.
Try to get change from a vending machine.
It gives all pennies.
"Nyoro~n"

Set out for a picnic.
It starts to rain.
"Nyoro~n"
You eat the food in the rain anyway.

You: Hello Best Friend, I got you some smoked cheese for your birthday!
Best Friend: I am lactose intolerant.
You (crestfallen): Nyoro~n...
You: Don't worry, I'll get you something even better, then!
Best Friend: But there is nothing better than smoked cheese.
You (realizing they are right): Nyoro~n...
Nyoro~n by NyoronTsuruya January 7, 2012
Related Words
Nkoro noromo noro- neorock Norovirus nooroo noroc noroigan Norona naoro

Norovirus 

a guarenteed way to lose 10 pounds in 24 hours, the closest to actual death you'll ever experience without a terminal illness or major accident. 24-36 hours of pooping and puking, fever, hallucinations, crying for your mommy, sweating, and bargaining with both Jesus and Satan to live.

Highly contagious. No medical treatment available besides starving yourself, and if you don't sanatize all handles with bleach afterwards you'll get it again.

Also known as Walking Dead Disease
" Dude what happened to Maddison , she was out for two days and now she looks like a hot zombie?"

"Norovirus bro. Don't touch her. She's deadly right now."
Norovirus by Motherofunicorns February 16, 2017
1. Shorthand for "no romance."
2. A person who prefers a platonic relationship between two characters, particularly Dana Scully and Fox Mulder on the X-Files.

antonym: shipper
"Mulder and Scully naked and humping each other?" said the aghast noromo. "How about... no."
noromo by queebuck July 7, 2005
Mistreated sad boi that needs to be saved from freaking hawkmoth
Kwami of transmission
i feel so bad for dis innocent boi
Friend: I feel so bad for Nooroo. He's treated so badly.
Me: Ikr, i wish he could be free :(
nooroo by a random hamilton fan October 16, 2020
A kind, generous person. One of the best you'll ever meet. They are amazing to be around.
"Hey, have you talked to Noro?"
"Yeah, they're so nice"
Noro by katsudon99 October 19, 2020
In Farsi, this word means "New Day" but is also referred to as the new year.
Happy Norooz Mohammad!
Norooz by pokemonpirates December 29, 2011