I.B.S 

Itchy Ball Syndrome.

1. One suffering from lack of sex, usually of the male gender.

Man 1:My god, I've got a bad case of I.B.S
Man 2: Wow, how long has it been, man?
Man 1: About a week.

I.B.S by Zhyre December 26, 2007

I.B.S. 

I.B.S. stands for Itchy Ball Syndrome. Applying to most males, when sweat forms inbetween the crevices of your ballsack and inner thigh. To releive yourself from this horrid disease a simple pinching motion to get your balls away from your leg is used.

It was about 100 degrees kelvin and i could feel that I.B.S. acting up already

I.B.S. by Soleau October 16, 2005

I.B.S. 

Itchy Ball Syndrome, occurs frequently for those with an excess amounts of fromunda cheese.

You see Mark, handling his I.B.S., poor guy, he was born taintless you know

I.B.S. by Frito_Pendejo June 18, 2007

I.B.S 

irritable bowel syndrome

caused by being too "sanitary" to use public bathrooms.

casues severe stomach aches until "relieved"

"i got I.B.S while i was in canada,damnit"

I.B.S by E.T December 20, 2006

I.B.S. 

Shortened form of "Itchy Butthole Syndrome". Caused most often by having multiple Anal Voids in a short period of time and/or an analingorgy.

I ate taco bell for two days straight. I had IBS for the next week.

I.B.S. by Stas April 5, 2003

I.B.S 

its an acronim for irrtable bitch syndrom.

my sister had a I.B.S mood yesterday

I.B.S by hiei9957 January 31, 2008

I.B.S. 

Identified Butt Snatcher: The close cousin of the UFO's. The aliens that drive the IBS have been identified and scientifically classified. Instead of probing the ass, they simply probe it with their own "Tool".

If youre lucky you will have a close encounter with the IBS and they will take you to Uranus

I.B.S. by bobby April 5, 2003