(1)As a greeting or as a farewell, to be used in general speak as a substitute for a much better, more difficult salutation.
(2) As a substitute for an affirmative response.
(3) As a substitute for virtually any interjection.
(1)Fred: I'll see you tomorrow, Chuck.
Chuck: OK Fred. Hizzoo!
(2)Fred: Are you going to the movies?
Chuck: Hizzoo!
(3) (A) Fred: Jeter just hit a Home
Run. Hizzoo!
(B) Fred: I won! I won! Hizzoo!
(C) Fred: Didn't that movie rock?
Chuck: Hizzoo!
Short-hand for the word floccinaucinihilipilification, meaning the estimation of something as valueless (encountered mainly as an example of one of the longest words in the English language).
Precedes or follows either a gratuitously disrespectful or honest remark, originated in New York City. Used in similar fashion to "no offense" or "to be honest," interchangeably.
Ya mans is wild buns, respectfully. Respectfully he's washed.
After school, The Modells on Jamaica Ave was active. Respectfully.