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Tweethole 

A person who uses Twitter way too much, think it's the best thing in the world and fills up your queue with crap. They tweet about what they're eating, when they take a shit, and other banal, boring and otherwise vapid drivel.
Jesus fucking Christy! I've gotten 20 tweets today from Bob about his shoes! What a Tweethole.
Tweethole by PoopyMcGee April 9, 2009
Related Words

Tweethearts

A couple who insist on having long sappy conversations on twitter to the annoyance of all who follow them
Jonh: I love you Heather! <3
Heather: I love you more John! <3
Me: Freaking Tweethearts, Will you just get a damn MSN convo already.
Tweethearts by Dr Simon Love February 16, 2010

tweethead 

1. A word that can be to describe certain people on twitter. People who tweet stupid, uninteresting mundain things. Similar to the meaning of:

-being a twit
-being a d*ckhead

or

2. A person who is addicted to Twitter, and twittering. Diehard twitters.
She can't even stop twittering to use the restroom or eat...tweets in her sleep. She is aciting like such a tweethead.

Tweetheart 

A person that does a great job tweeting via twitter.

Someone who uses twitter a lot.
Henry is such a tweetheart.
Tweetheart by JunkyRhythm April 3, 2009

tweetheart 

1. A person who is much loved in Twitter
2. A sweetie or any well-liked individual in Twitter
She is the tweetheart of my life.
tweetheart by timlight January 30, 2010
That girl at work who sits on twitter all day not working while you slave away for the man.
I can't believe Krystal twittered that I spilled ketchup on my pants at lunch? What a tweetho!
tweetho by cantalop March 4, 2009