toxic megacolon 

Acute dilation of the colon, seen in ulcerative colitis.

"You've got toxic megacolon, ASSFACE!!"

toxic megacolon by angelvs August 4, 2007

Toxic Megacolons 

The most dominant ROTO baseball team ever assembled, without collusion, via skilled drafting, shrewd trades, and timely waiver acquisitions. The team took the lead in its 12 team league in mid-April and never looked back, finishing a dominating 20.5 points ahead of the runner-up. Its murderous batting lineup finished 1st in 5 of 6 offensive categories (R, HR, RBI, AVG, OPS) and 2nd in steals. Its dominant pitchers carried the team to 1st in ERA and WHIP, 2nd in SAVES and HOLDS, and 5th in WINS and K's. The indomitable lineup, in its optimal form, was as follows:

C: Brian McCann, ATL
1B: Albert Pujols, StL
2B: Chase Utley, PHI
3B: Aramis Ramirez, CHC
SS: Jose Reyes, NYM
OF: Lance Berkman, HOU
OF: Carlos Lee, TEX
OF: Matt Holiday, COL
UT: Troy Glaus, TOR
Bench: Hideki Matsui, NYY; Jason Varitek, BOS; Corey Patterson, BAL; Kevin Youkilis, BOS; Juan Rivera LAA

SP: Roy Halladay, TOR
SP: Andy Pettitte, HOU
SP: Jered Weaver, LAA
RP: BJ Ryan, TOR
RP: Akinori Otsuka, TEX
RP: Tom Gordon, PHI
P: Todd Jones, DET
P: Joel Zumaya, DET
P: John Lackey, LAA
Bench: Esteban Loaiza, Jon Lester, Mike Stanton

Carlos Lee was acquired in June for Pat Burrell and Ken Griffey Jr. to solidify and streamline the lineup.

Ladies and Gentlemen, the greatest ROTO team of all time!!! Wooooo!!

Man, there is no way we can compete with the Toxic Megacolons. That team is a juggernaut!

Toxic Megacolons by Crew Middle Fork December 7, 2006

toxic mega-colon 

A form of diarrhea caused by bacteria Clostridium difficil, that lives in poop.

Aaron can't go out tonight. He's got toxic mega-colon.

toxic mega-colon by moneypenny07 March 21, 2009

Grindset

The grindset is a contemporary ideology of self-exploitation disguised as strength, deeply tied to the aesthetics of the “sigma male” and to new digital forms of patriarchy. It promotes the idea that human worth depends on productivity, economic success, absolute emotional control, and the ability to work endlessly, turning vulnerability, rest, community, and tenderness into signs of weakness. Beneath its rhetoric of discipline and power often lies a profound inability to relate healthily to pain, fragility, and human interdependence.

“That’s the grindset, brother. While weak men sleep and complain, sigma males stay disciplined, work in silence, suppress emotions, and build power while everyone else wastes time chasing comfort.”

Grindset by Omega-Male May 22, 2026

jerb 

well known from south park
rednecks get angrry that future folk took there jobs so they yell
They took ouare jerbs!

Them future folk took ouare jerbs!

jerb by Jimberley Kim April 7, 2005

Cheeks 

An Irish phrase meaning shit, derived from ass
(Not to be confused with the literal description of one's buttocks)

"Did you hear the song Aylek$ dropped?"
"Hardly. Her music is absolute cheeks."

"My boyfriend say LaFlame is cheeks."
"Tell your boyfriend I said it's his mixtape that's cheeks."

Cheeks by thecartisan April 26, 2020

sans sheriff 

Lawless use of fonts or typography, with no regard to aesthetics or legibility

I'm putting this CV straight in the bin. Written totally sans sheriff.

sans sheriff by Jamarley July 3, 2019