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originally came from the "spot" a place to get heroine or crack from Chicago's west side. " just starting after harlem ave. off 290"
T weso and ice pick hit a lick now they are going to the the spizzle to cop.
spizzle by Vdux August 26, 2007
man i had some of the bomb 0 gravity spizzle and i was fucked up
Spizzle by Lytez Out August 28, 2011

spizzled 

1.when someone is talking, and they accidentally spit on you.
2. when your casually walking and someone randomly spits on you.
1. "doood you just spizzled on me! gross!"
2."i was walkin and some mutha fucka spit a big one at me!"
spizzled by jandraka October 9, 2007

Spizzler 

Noun- someone who is basically a lame-o they wont do anything spontaneous or on a night where school is the next day.
Me: Hey lets go to Emily's for movie night in like an hour!

Spizzler: Nah I can't we have school tomorrow.

Me: Yea but its not an all night thing just till like 10:00 or 11:00

Spizzler: Yea but its such late notice and I am kinda sleepy so gonna have to pass :(
Spizzler by Brown Bear123545321 February 23, 2009

skizzlez 

1) Another word for skills.
2) When a guy stands straight up and a girl gets on her knees with a bag of skittles and the guy proceeds to fuck the skittles and the girl eats the cum and all.
3) When a girl (or a gay guy depending on how you are) is on her knees and gives a guy a blow job with skittles in her mouth and the guy's penis turns different colors.
Man, my girl friend gave me some skizzlez and my penis turned red, green, and purple.
skizzlez by Bud Tole/Asifer Deushon November 21, 2009
A sip or otherwise limited quantity of food or beverage.
Aw dude, lemmie get a spizzle of that Gatorade, my cottonmouth is killin me
Spizzle by Bruno F'Sho May 13, 2005