The nickname for new no-longer-science-fiction-related TV network Syfy that was once called the Sci-Fi Channel. Syphy is phonetically equivalent to Syfy, but expounds on the obvious connection to venereal diseases.
Syphy is used among ex-fans of the network and SF/science fiction aficionados who believe that the re-branding press release was a slap in the face for anyone who enjoys sci-fi.
Someone who has contracted syphillis, gonorea, herpes, and aids because they are such a slut and whore who commonly sleeps with carnies and men of questonable status.