The nickname for new no-longer-science-fiction-related TV network Syfy that was once called the Sci-Fi Channel. Syphy is phonetically equivalent to Syfy, but expounds on the obvious connection to venereal diseases.

Syphy is used among ex-fans of the network and SF/science fiction aficionados who believe that the re-branding press release was a slap in the face for anyone who enjoys sci-fi.
There is another bad monster movie on Syphy.

TV Watcher #1: What's on Syphy tonight?
TV Watcher #2: That sounds like an STD.
TVW1: Huh. You're right, I guess it does!
by Cricket_B March 18, 2009
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1: Having a variable rainbow of sexually transmitted diseases. 2: Slut
Sally is such a slut, i bet that she has gona-herpa-syphi-aids!
by Ken Kearns January 25, 2008
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Shortened version of the STD's ghonnorea, herpes, and syphilis. Usually refering to someone as being easy or dirty.
I'm pretty sure Joe has ghona-herpe-syphi-litis. That boy has been around the block more than a few times.
by KrazySkaterChick March 19, 2008
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