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main hoe 

A Main Hoe is the main girl you would do something for. It can be caring about her and knowing she's got your back too or sticking up for her when something bad happens.
You're there for your main hoe until the end.
Bob: "Hey Jim, who is your main hoe?"
Jim: "Lola is my main hoe. I'd do anything for that girl."
main hoe by Mario&Luigi March 29, 2014

main hoe 

A mans primary woman. This is the girl he is willing to actually stand up for and is different from his bitchalong.
If anyone tries to put any moves on my main hoe then it's ownage time.
main hoe by ownagetime March 18, 2008

Main Hoes 

Mainhoes- main hoes are your ride or die if somebody get buck on one of them you all buck back if somebody try to jump y'all you all better beat there ass down!!! Because y'all are the main hoes and if you fuck with the main hoes you get the MAIN HOES!!!! Straight Facts!!!
Friend #1 y'all know I love y'all oso much and y'all are my best friends

Friend #2 yessss that's why we are the main hoes

Friend #3 yess and whoever try to fuck with us imma burn there house down

Friend #4 ayeee main hoes Gang Gang
Friend #5 Gang Gang Main Hoes

Main hoe 

Erin Holman is my main hoe not pedro would never cheat on and also puts spray tan on ya that makes it look like your severely sun burnt
Erin is my main hoe

main house 

When you have multiple houses, the main one.
For example, Bush's main house is a ranch in Texas. It used to be the White House.

horny on main 

a slang term for posting or engaging with sexual posts on your main social media account, rather than a secondary one that you’d usually use for that purpose. the phrased spawned on tumblr, after ted cruz liked a vore fetish drawing on his main, verified account.
“real men don’t wait until 4am to get horny on main

“@_____ y’all nasty
horny on main by xylobones February 22, 2018
Word of the Day on May 3, 2019