Definitions by Mario&Luigi

main hoe 

A Main Hoe is the main girl you would do something for. It can be caring about her and knowing she's got your back too or sticking up for her when something bad happens.
You're there for your main hoe until the end.

Bob: "Hey Jim, who is your main hoe?"
Jim: "Lola is my main hoe. I'd do anything for that girl."

main hoe by Mario&Luigi March 29, 2014