To have been rendered less of a man, or been made to feel much less of a man through humiliation. This term is most often used to describe a male douchebag who has been pussywhipped by his woman.
The fact that lame Ed has chosen to neglect his friends and be home before midnight on a Friday night is proof that he has allowed himself to become completely emasculated by his girlfriend.
"Sridher what was up with you last night"
"Dude, I just went to a strip club.. kind crossed and ended up going home with Cindy Crawford"
"Wow, seems like you immaculated hard last nite man"