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According to my Spanish book, it means "Jeez!". It's more like a general expression of surprise, annoyance or exasperation.
"Hijole! Why did that puta even bother calling him?"
hijole by Lolita Alvarezz May 12, 2006
Related Words
hisole hijole Hisle hijoley hisale Hisler hisollumi hisore hissle Histle
1. (n.) a marijuana joint, bone, paper plane etc.
2. (v.) the soft sound between a rustle and a hiss (like the sound of a sparked j), the act of hissling
3. (n.) a small amount, a quick toke

extra: Chrisstle: a cross-joint
1. "Finna spark a hissle right quick before class."
2. a. "Listen to it hissle!" b. "Ima go hissle right now, straight killa no filla."
3. "what are you reachin for?" "Can I get a lil hissle on that?"
noun
(haɪ'sʊl)

An old, bald and —as if that's not depressing enough— Jewish male whose primary defense mechanisms against constant embarrassment are self-deprecation and the liberal use of anti-semitic humor.
"Hey, I just saw a hisle in front of the deli warning children about wooden nickels."
Hisle by LessJewThanYou May 21, 2019

Adolf Hissler 

A term used to describe black and white cats that have a small black patch under their nose, resembling the patch of hair under that of Adolf Hitler, however they do not have anything in else in common with him. The term "Hissler" is a play on words of "Hitler", with "Hiss" being put in place of the beginning. This is a reference to the hissing sound a cat makes when angry, which coincidentally, Hitler often was. (Or at least he sounded like it since he did a great deal of shouting.)
you're cat looks familiar

Yeah, he's a feline Adolf Hissler
Christ-killer
Hisle by DisappointedMoses May 3, 2019
Australian slang. Used to start a sentence or express happiness, surprise, admiration or pleasure. Can also be written or pronounced "izole."
Hizole, I'm headin' out yarrabah way.

Hizole! That was a pretty chay backflip!

Hizole! I wasn't expecting to see you tonight!

Hizole, did you see him skull that JD? What a chay cunt!
Hizole by Auxen October 8, 2012