hijole

According to my Spanish book, it means "Jeez!". It's more like a general expression of surprise, annoyance or exasperation.

"Hijole! Why did that puta even bother calling him?"

by Lolita Alvarezz May 1, 2006

hijole

"Son of a..."
It's a shortened version of hijo de puta (“son of a bitch”).

Glottis: We have to find the key!
Manny: Hijole!

by Master Speed November 3, 2016