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According to my Spanish book, it means "Jeez!". It's more like a general expression of surprise, annoyance or exasperation.
"Hijole! Why did that puta even bother calling him?"
by Lolita Alvarezz May 01, 2006
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May 14 Word of the Day
Intelligence agency term for "psychological operation". A government or corporate-sponsored operation, usually taking the form of a "terrorist attack" or "crazed gunman on a spree", with the intent of panicking the public into demanding more police and laws inhibiting freedom. Psyops are usually carried out by drugging a civilian or group of civilians with aggression-promoting drugs, psyching them up, arming them, and sending them out to commit mayhem. Government-sponsored terrorism. See also blackshirts, conspiracy
Person A: Man, that nutcase Martin Bryant guy shot 35 people in Tasmania!

Person B: No, he wasn't a nutcase, that was just a psyop so the government could have an excuse to ban guns.
by Mystikan April 11, 2006
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"Son of a..."
It's a shortened version of hijo de puta (“son of a bitch”).
Glottis: We have to find the key!
Manny: Hijole!
via giphy
by Master Speed November 03, 2016
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