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A case of the fuck-its 

Noun. A temporary mindset shift from somewhat obsessing about multiple, seemingly important but annoying issues to the state of not caring at all. After dealing with the same persistent situation over a period of time, the conscious or unconscious decision to not be bothered anymore. Giving up.
After waiting on hold for 40 minutes for a representative while making dinner and trying to get his son to clean his room, John developed a case of the fuck-its, hung up, cracked a beer and sat down to watch some cat videos.

Friday Fuck-Its 

The overwhelming sense of not giving a crap about the horrendous amount of work and deadlines you have simply because it's Friday.
M1 - "Hey man, you wanna duck out early and go play some disc golf?"
M2 - "Don't you have a big report due on Monday?"
M1 - "Yeah, but I've got a case of the Friday Fuck-Its. I won't get anything done anyway."

the fuck its 

The fuck its also known as fuck its are a medical anomally that occur when your laziness gets the better of you. Usually happens when pressing matters are soon to arrive, such as projects due the next day or chores to be done around the house.
Symptoms include:
Coughing while saying fuck it.
Laziness.
Boredom.
Hunger.
The desire to go smoke weed or pack a lip.
Oh crap i have a project due tomorrow morning. Alright i have to do this.
*5 minutes later
Cough fuck it Cough oh man i got the fuck its cough cough fuck it enhhh fuck it wheres that skoal.
the fuck its by meher1312 April 27, 2011

the fuck its 

greg wanted me to help him build his pool today but i got a case of the fuck its and didnt want to
the fuck its by travelsizedjoe August 1, 2008

its fuck off o'clock

When you just wake up and someone wants to talk to you.
Hey, Your mother was cremated
Its fuck off o'clock, shut up.

I'm [fuck]ing this cat, so shut up and hold its tail 

The meaning of this phrase is to alert co-workers, on-lookers, passers-by, and anyone else in a group, large or small, who is in charge of a given scenario.
Bryan: Well, what if we approach this problem from a different perspective?

Debra: I'm fucking this cat, so just shut up and hold its tail!